BLK 抗体 (pTyr501)
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北京 101111
Quick Overview for BLK 抗体 (pTyr501) (ABIN7139015)
抗原
See all BLK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr501
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原理
- Phospho-BLK (Tyr501) Antibody
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交叉反应
- 小鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK.
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亚型
- IgG
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anti-B Lymphoid Tyrosine Kinase (BLK) (AA 241-494) antibody
BLK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-90) antibodyBLK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7A12 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibodyBLK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E5-3A8 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 9D10B7 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-30), (N-Term) antibodyBLK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03107 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-280) antibodyBLK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibodyBLK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 9D10D1 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (N-Term) antibodyBLK 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BLK (B Lymphoid Tyrosine Kinase (BLK))
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别名
- BLK
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背景
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Background:
Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor.
Islam K.B., J. Immunol. 154:1265-1272(1995).
Drebin J.A.,Oncogene 10:477-486(1995).
Greenman C.,Nature 446:153-158(2007).Aliases: B lymphocyte kinase antibody, B lymphoid tyrosine kinase antibody, Blk antibody, BLK nonreceptor tyrosine kinase antibody, BLK_HUMAN antibody, EC 2.7.10.2 antibody, MGC 10442 antibody, MGC10442 antibody, MODY 11 antibody, MODY11 antibody, P55 BLK antibody, p55-BLK antibody, Tyrosine kinase B lymphocyte specific antibody, Tyrosine protein kinase antibody, Tyrosine-protein kinase BLK antibody
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UniProt
- P51451
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途径
- Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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