BCAR1 抗体 (pTyr410)
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北京 101111
Quick Overview for BCAR1 抗体 (pTyr410) (ABIN7139001)
抗原
See all BCAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr410
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原理
- Phospho-BCAR1 (Tyr410) Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas .
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亚型
- IgG
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anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (AA 1-240) antibody
BCAR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) antibodyBCAR1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) antibodyBCAR1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (AA 68-218) antibodyBCAR1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (pTyr410) antibodyBCAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (Internal Region) antibodyBCAR1 适用: 人, 小鼠 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (Tyr410) antibodyBCAR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (pTyr410) antibodyKD Validated BCAR1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3870 unconjugated Recombinant Antibody
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (Internal Region) antibodyVerified BCAR1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) antibodyKD Validated BCAR1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3690 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))
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别名
- BCAR1
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背景
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Background:
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
Katarzyna Modzelewska, J. Biol. Chem., Dec 2006, 281: 37527 - 37535.
Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006, 291: H2857 - H2863.
Sangkil Nam, Cancer Res., Oct 2005, 65: 9185 - 9189.
Norikazu Yamana, Mol. Cell. Biol., Sep 2006, 26: 6844 - 6Aliases: BCAR 1 antibody, Bcar1 antibody, BCAR1_HUMAN antibody, Breast cancer anti estrogen resistance 1 antibody, Breast cancer anti estrogen resistance 1 protein antibody, Breast cancer anti-estrogen resistance protein 1 antibody, CAS antibody, Cas scaffolding protein family member 1 antibody, CAS1 antibody, Cass1 antibody, Crk associated substrate antibody, Crk associated substrate p130Cas antibody, CRK-associated substrate antibody, CRKAS antibody, FLJ12176 antibody, FLJ45059 antibody, p130cas antibody
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UniProt
- P56945
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
抗原
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