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DOK2 抗体 (pTyr299)

DOK2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138971
发货至: 中国
  • 抗原 See all DOK2 抗体
    DOK2
    抗原表位
    • 22
    • 21
    • 15
    • 9
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr299
    适用
    • 110
    • 78
    • 18
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    宿主
    • 124
    • 1
    克隆类型
    • 124
    • 1
    多克隆
    标记
    • 39
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    This DOK2 antibody is un-conjugated
    应用范围
    • 98
    • 52
    • 52
    • 39
    • 25
    • 20
    • 12
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2.
    亚型
    IgG
  • 应用备注
    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    DOK2
    别名
    DOK2 (DOK2 产品)
    别名
    DokR antibody, Frip antibody, Dok-2 antibody, p56DOK antibody, p56dok-2 antibody, docking protein 2 antibody, DOK2 antibody, Dok2 antibody
    背景

    Background:

    DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation

    Feng Cong, et,al. (1999) Mol. Cell. Biol , 19: 8314 - 8325.
    Serge Lemay, et,al. (2000) Mol. Cell. Biol , 20: 2743 - 2754.
    Ute Schaeper, et,al.(2000) J. Cell Biol , 149: 1419.
    Miyuki Honma, et,al. (2006) Genes Cells, 11: 143 - 151.

    Aliases: Docking protein 2 56 kDa antibody, Docking protein 2 antibody, DOK 2 antibody, DOK R antibody, DOK2 antibody, DOK2_HUMAN antibody, Downstream of tyrosine kinase 2 antibody, OTTHUMP00000161710 antibody, OTTHUMP00000224923 antibody, p56(dok 2) antibody, p56(dok-2) antibody, p56dok 2 antibody, p56DOK antibody, p56dok2 antibody

    UniProt
    O60496
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