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ABL1 抗体 (pTyr204)

This anti-ABL1 antibody is a 兔 多克隆 antibody detecting ABL1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7138953
发货至: 中国

Quick Overview for ABL1 抗体 (pTyr204) (ABIN7138953)

抗原

See all ABL1 抗体
ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ABL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    pTyr204

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of tyrosine 204 (K-L-Y(p)-V-S) derived from Human c-Abl.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

    别名

    ABL1

    背景

    Background:

    Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation), ANXA1 (involved in membrane anchoring), DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling), or MAPT and PXN (microtubule-binding proteins).

    Meyn MA, et al. (2006) J Biol Chem 281, 30907-16
    Steen H, et al. (2003) Mol Cell Proteomics 2, 138-45
    Salomon AR, et al. (2003) Proc Natl Acad Sci U S A 100, 443-8

    Aliases: Abelson murine leukemia viral oncogene homolog 1 antibody, Abelson tyrosine protein kinase 1 antibody, Abl 1 antibody, ABL antibody, ABL proto oncogene 1 non receptor tyrosine kinase antibody, ABL1 antibody, ABL1_HUMAN antibody, bcr/abl antibody, bcr/c abl oncogene protein antibody, c ABL antibody, c abl oncogene 1 non receptor tyrosine kinase antibody, c abl oncogene 1 receptor tyrosine kinase antibody, c ABL1 antibody, JTK7 antibody, p150 antibody, Proto oncogene tyrosine protein kinase ABL1 antibody, Proto-oncogene c-Abl antibody, Tyrosine-protein kinase ABL1 antibody, v abl Abelson murine leukemia viral oncogene homolog 1 antibody, v abl antibody

    UniProt

    P00519

    途径

    Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
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