Phospholipase D2 抗体 (pTyr169)
Quick Overview for Phospholipase D2 抗体 (pTyr169) (ABIN7138945)
抗原
See all Phospholipase D2 (PLD2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr169
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of tyrosine 169(E-N-Y(p)-L-N) derived from Human PLD2.
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亚型
- IgG
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应用备注
- WB:1:500-1:1000, IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Phospholipase D2 (PLD2)
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别名
- PLD2
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背景
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Background:
Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.
Steed P.M., FASEB J. 12:1309-1317(1998).
Lopez I., J. Biol. Chem. 273:12846-12852(1998).
Divecha N., EMBO J. 19:5440-5449(2000).Aliases: Choline phosphatase 2 antibody, EC 3.1.4.4 antibody, hPLD 2 antibody, hPLD2 antibody, mPLD2 antibody, Phosphatidylcholine hydrolyzing phospholipase D2 antibody, Phosphatidylcholine-hydrolyzing phospholipase D2 antibody, Phospholipase D2 antibody, PhospholipaseD2 antibody, PLD 2 antibody, PLD1C antibody, Pld2 antibody, PLD2_HUMAN antibody, Pldc antibody, rPLD2 antibody
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UniProt
- O14939
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途径
- RTK signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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