BLM 抗体 (pThr99)
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北京 101111
Quick Overview for BLM 抗体 (pThr99) (ABIN7138888)
抗原
See all BLM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr99
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原理
- Phospho-BLM (Thr99) Antibody
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of threonine 99 (Q-E-T(p)-Q-R) derived from Human Bloom Syndrome.
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亚型
- IgG
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anti-Bloom Syndrome RecQ Like Helicase (BLM) (C-Term) antibody
BLM 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (AA 1196-1295) antibodyBLM 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (N-Term) antibodyBLM 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (AA 1196-1295) antibodyBLM 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (AA 1054-1082), (C-Term) antibodyBLM 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB25943 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BLM (Bloom Syndrome RecQ Like Helicase (BLM))
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别名
- BLM
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背景
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Background:
Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).
Ellis N.A., Cell 83:655-666(1995).
Karow J.K., J. Biol. Chem. 272:30611-30614(1997).
Pichierri P., EMBO J. 23:3154-3163(2004).Aliases: Blm antibody, BLM_HUMAN antibody, Bloom syndrome antibody, Bloom syndrome protein antibody, Bloom syndrome RecQ helicase like antibody, BS antibody, DNA helicase antibody, DNA helicase RecQ like type 2 antibody, MGC126616 antibody, MGC131618 antibody, MGC131620 antibody, RECQ 2 antibody, RECQ like antibody, RecQ like type 2 antibody, RecQ protein like 3 antibody, RecQ protein-like 3 antibody, RecQ-like type 2 antibody, RecQ2 antibody, RECQL 2 antibody, RECQL 3 antibody, RECQL2 antibody, RECQL3 antibody, type 2 antibody
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UniProt
- P54132
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途径
- DNA Damage Repair
抗原
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