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SP1 抗体 (pThr739)

SP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138879
发货至: 中国
  • 抗原 See all SP1 抗体
    SP1 (Sp1 Transcription Factor (SP1))
    抗原表位
    • 21
    • 11
    • 11
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr739
    适用
    • 87
    • 60
    • 39
    • 11
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    宿主
    • 89
    • 13
    • 3
    克隆类型
    • 84
    • 21
    多克隆
    标记
    • 71
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SP1 antibody is un-conjugated
    应用范围
    • 90
    • 46
    • 45
    • 36
    • 21
    • 16
    • 13
    • 13
    • 12
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    人, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of threonine 739 (T-A-T(p)-P-S) derived from Human SP1
    亚型
    IgG
    Top Product
    Discover our top product SP1 Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SP1 (Sp1 Transcription Factor (SP1))
    别名
    SP1 (SP1 产品)
    背景

    Background: Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-a G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

    Thiesen HJ,et al.(1990)Nucleic Acids Res.18(11):3203-9.
    Zutter MM,et al.(1997) Blood.90(2):678-89.
    Lou Z,et al.(2005)Cancer Res.65(3):1007-17

    Aliases: SP 1 antibody, SP1 antibody, Sp1 transcription factor antibody, SP1_HUMAN antibody, Specificity protein 1 antibody, Transcription factor Sp1 antibody, TSFP 1 antibody, TSFP1 antibody

    UniProt
    P08047
    途径
    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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