电话:: +86 (0512) 65829739
传真:: +86 (010) 6788 5057
电子邮件:: orders@antibodies-online.cn

我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

APP 抗体 (pThr668)

This anti-APP antibody is a 兔多克隆 antibody detecting APP in WB 和 ELISA. Suitable for 人.

Western blot analysis of extracts from Hela cells, treated with Noc or calf intestinal phosphatase (CIP), using APP (Phospho-Thr668) Antibody. (APP 抗体 (pThr668))

Western blot analysis of extracts from mouse brain tissue using APP(Phospho-668) Antibody(Lane 2) and the same antibody preincubated with blocking peptide(Lane1). (APP 抗体 (pThr668))

2 images

产品编号 ABIN7138873

发货至: 中国

Datasheet as PDF

Quick Overview for APP 抗体 (pThr668) (ABIN7138873)

抗原

See all APP 抗体

APP (Amyloid beta (A4) Precursor Protein (APP))

适用

259
117
112
11
9
8
8
8
8
7
6
5
4
4
3
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

175
26
20
18
7
6
4
4
4
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
1

This APP antibody is un-conjugated

应用范围

200
150
96
52
52
49
44
42
33
29
15
6
5
5
3
2
2
1
1
1
1

Western Blotting (WB), ELISA

Discover our top product APP Primary Antibody

抗原表位
30

27

24

22

17

16

11

8

8

8

8

7

6

5

5

5

5

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr668

交叉反应

人, 小鼠, 大鼠

纯化方法

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

免疫原

Peptide sequence around phosphorylation site of threonine 668 (A-V-T(p)-P-E) derived from Human APP.

亚型

IgG
anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody
APP 适用: 人 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) antibody
APP 适用: 人, 小鼠 WB, ELISA, IHC, IF, FM 宿主: 兔 Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (AA 666-670) antibody
APP 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (AA 18-270) antibody
APP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody
APP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) antibody
KO Validated APP 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (AA 381-480) antibody
APP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (pThr668) antibody
APP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) antibody
APP 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody
APP 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB:1:500-1:1000,

限制

仅限研究用
状态

Liquid

缓冲液

Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

APP (Amyloid beta (A4) Precursor Protein (APP))

别名

APP

背景

Background:
APP encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Hung, A.Y. and Selkoe, D.J. (1994) EMBO J. 13, 534-542.
Suzuki, T. et al. (1994) EMBO J. 13, 1114-1122
Ando, K. et al. (1999) J. Neurosci. 19, 4421-4427.
Iijima, K.I. et al. (2000) J. Neurochem. 75, 1085-1091
Aliases: A4 antibody, A4_HUMAN antibody, AAA antibody, ABETA antibody, ABPP antibody, AICD-50 antibody, AICD-57 antibody, AICD-59 antibody, AID(50) antibody, AID(57) antibody, AID(59) antibody, Alzheimer disease amyloid protein antibody, Amyloid intracellular domain 50 antibody, Amyloid intracellular domain 57 antibody, Amyloid intracellular domain 59 antibody, APP antibody, APPI antibody, Beta amyloid protein 42 antibody, Beta APP42 antibody, Beta-APP40 antibody, Beta-APP42 antibody, C31 antibody, Cerebral vascular amyloid peptide antibody, CVAP antibody, Gamma-CTF(50) antibody, Gamma-CTF(57) antibody, Gamma-CTF(59) antibody, PN-II antibody, PreA4 antibody, Protease nexin-II antibody, S-APP-alpha antibody, S-APP-beta antibody

UniProt

P05067

途径

Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour

You are here: