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c-MYC 抗体 (pThr358)

This anti-c-MYC antibody is a 兔 多克隆 antibody detecting c-MYC in WB, IHC, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7138839
发货至: 中国

Quick Overview for c-MYC 抗体 (pThr358) (ABIN7138839)

抗原

See all c-MYC (MYC) 抗体
c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

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宿主

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克隆类型

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多克隆

标记

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This c-MYC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    pThr358

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of threonine 358 (R-R-T(p)-H-N) derived from Human Myc.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

    别名

    MYC

    背景

    Background: Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.

    Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702.
    Blackwood E M, et al. (1991) Science. 251:1211-1217.
    Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182.
    Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699.

    Aliases: AU016757 antibody, Avian myelocytomatosis viral oncogene homolog antibody, bHLHe39 antibody, c Myc antibody, Cellular myelocytomatosis oncogene antibody, Class E basic helix-loop-helix protein 39 antibody, MGC105490 antibody, MRTL antibody, Myc antibody, Myc protein antibody, Myc proto oncogene protein antibody, Myc proto-oncogene protein antibody, myc-related translation/localization regulatory factor antibody, MYC_HUMAN antibody, Myc2 antibody, myca antibody, MYCC antibody, Myelocytomatosis oncogene a antibody, Myelocytomatosis oncogene antibody, Niard antibody, Nird antibody, oncogene c-Myc antibody, Oncogene Myc antibody, OTTHUMP00000158589 antibody, OTTHUMP00000227763 antibody, Proto-oncogene c-Myc antibody, Protooncogene homologous to myelocytomatosis virus antibody, RNCMYC antibody, Transcription factor p64 antibody, Transcriptional regulator Myc-A antibody, V-Myc avian myelocytomatosis viral oncogene homolog antibody, v-myc myelocytomatosis viral oncogene homolog (avian) antibody, zc-myc antibody

    UniProt

    P01106

    途径

    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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