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XIAP 抗体 (pSer87)

This anti-XIAP antibody is a 兔 多克隆 antibody detecting XIAP in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7138763
发货至: 中国

Quick Overview for XIAP 抗体 (pSer87) (ABIN7138763)

抗原

See all XIAP 抗体
XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

适用

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宿主

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克隆类型

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多克隆

标记

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This XIAP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    pSer87

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of serine87(K-V-S(p)-P-N) derived from Human XIAP .

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

    别名

    XIAP

    背景

    Background:

    Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state.

    Huang X, Wu Z, Mei Y, Wu M (2013)EMBO J 32, 2204-16. Bornhauser BC, et al. (2007) Blood 110, 2084-91.Dan HC, et al. (2004)J Biol Chem 279, 5405-12.

    Aliases: AP 13 antibody, API3 antibody, Apoptosis Inhibitor 3 antibody, Baculoviral IAP repeat containing 4 antibody, Baculoviral IAP Repeat Containing Protein 4 antibody, Baculoviral IAP repeat-containing protein 4 antibody, BIRC 4 antibody, BIRC4 antibody, E3 ubiquitin-protein ligase XIAP antibody, hIAP-3 antibody, hIAP3 antibody, HILP antibody, IAP 3 antibody, IAP like protein antibody, IAP-3 antibody, IAP-like protein antibody, IAP3 antibody, ILP 1 antibody, ILP antibody, ILP1 antibody, Inhibitor of apoptosis protein 3 antibody, Inhibitor of Apoptosis X Linked antibody, Mammalian IAP Homologue A antibody, MIHA antibody, X linked IAP antibody, X linked inhibitor of apoptosis antibody, X linked inhibitor of apoptosis E3 ubiquitin protein ligase antibody, X linked inhibitor of apoptosis protein antibody, X-linked IAP antibody, x-linked inhibitor of apopotosis proteins antibody, X-linked inhibitor of apoptosis protein antibody, Xiap antibody, XIAP_HUMAN antibody, XLP2 antibody

    UniProt

    P98170

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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