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DDIT3 抗体 (pSer30)

DDIT3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138755
发货至: 中国
  • 抗原 See all DDIT3 抗体
    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
    抗原表位
    • 16
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    pSer30
    适用
    • 113
    • 78
    • 64
    • 5
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    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
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    宿主
    • 109
    • 11
    克隆类型
    • 97
    • 23
    多克隆
    标记
    • 58
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    This DDIT3 antibody is un-conjugated
    应用范围
    • 97
    • 53
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    • 9
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    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of serine30(V-L-S(p)-S-D) derived from Human CHOP .
    亚型
    IgG
    Top Product
    Discover our top product DDIT3 Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
    别名
    DDIT3 (DDIT3 产品)
    背景

    Background:

    Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L.

    Ubeda M, Habener JF (2003) J Biol Chem 278, 40514-20

    Aliases: C/EBP homologous protein antibody, C/EBP Homology Protein antibody, C/EBP zeta antibody, C/EBP-homologous protein 10 antibody, C/EBP-homologous protein antibody, CCAAT/enhancer binding protein homologous protein antibody, CEBPZ antibody, CHOP 10 antibody, CHOP antibody, CHOP-10 antibody, CHOP10 antibody, DDIT 3 antibody, DDIT-3 antibody, Ddit3 antibody, DDIT3_HUMAN antibody, DNA Damage Inducible Transcript 3 antibody, DNA damage-inducible transcript 3 protein antibody, GADD 153 antibody, GADD153 antibody, Growth Arrest and DNA Damage Inducible Protein 153 antibody, Growth arrest and DNA damage inducible protein GADD153 antibody, Growth arrest and DNA damage-inducible protein GADD153 antibody, MGC4154 antibody

    UniProt
    P35638
    途径
    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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