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DDIT3 抗体 (pSer30)

This anti-DDIT3 antibody is a 兔 多克隆 antibody detecting DDIT3 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7138755
发货至: 中国

Quick Overview for DDIT3 抗体 (pSer30) (ABIN7138755)

抗原

See all DDIT3 抗体
DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

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宿主

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克隆类型

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多克隆

标记

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This DDIT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    pSer30

    交叉反应

    人, 小鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of serine30(V-L-S(p)-S-D) derived from Human CHOP .

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

    别名

    DDIT3

    背景

    Background:

    Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L.

    Ubeda M, Habener JF (2003) J Biol Chem 278, 40514-20

    Aliases: C/EBP homologous protein antibody, C/EBP Homology Protein antibody, C/EBP zeta antibody, C/EBP-homologous protein 10 antibody, C/EBP-homologous protein antibody, CCAAT/enhancer binding protein homologous protein antibody, CEBPZ antibody, CHOP 10 antibody, CHOP antibody, CHOP-10 antibody, CHOP10 antibody, DDIT 3 antibody, DDIT-3 antibody, Ddit3 antibody, DDIT3_HUMAN antibody, DNA Damage Inducible Transcript 3 antibody, DNA damage-inducible transcript 3 protein antibody, GADD 153 antibody, GADD153 antibody, Growth Arrest and DNA Damage Inducible Protein 153 antibody, Growth arrest and DNA damage inducible protein GADD153 antibody, Growth arrest and DNA damage-inducible protein GADD153 antibody, MGC4154 antibody

    UniProt

    P35638

    途径

    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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