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Glutamate Receptor 1 抗体 (pSer836)

The 兔 多克隆 anti-Glutamate Receptor 1 antibody is suitable to detect Glutamate Receptor 1 in samples from 人. It has been validated for WB 和 ELISA.
产品编号 ABIN7138713
发货至: 中国
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Quick Overview for Glutamate Receptor 1 抗体 (pSer836) (ABIN7138713)

抗原

See all Glutamate Receptor 1 (GLUR1) 抗体
Glutamate Receptor 1 (GLUR1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Glutamate Receptor 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    pSer836

    原理

    Phospho-GRIA1 (Ser836) Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of serine 836 (S-E-Sp-K-R) derived from Human GluR1

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Glutamate Receptor 1 (GLUR1)

    别名

    GRIA1

    背景

    Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of a-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Emamian ES, et al. (2004) J Neurosci. 24(7): 1561-4
    Palmer, C.L. et al. (2005) Pharmacol. Rev. 57, 253-277.

    Aliases: GLUR 1 antibody, GLUR A antibody, AMPA 1 antibody, AMPA selective glutamate receptor 1 antibody, AMPA-selective glutamate receptor 1 antibody, GluA1 antibody, GLUH1 antibody, GluR K1 antibody, GluR-1 antibody, GluR-A antibody, GluR-K1 antibody, GLUR1 antibody, GLURA antibody, GluRK1 antibody, Glutamate receptor 1 antibody, Glutamate receptor ionotropic AMPA 1 antibody, Glutamate receptor ionotropic antibody, Glutamate receptor, ionotropic, AMPA 1 antibody, Gria1 antibody, GRIA1_HUMAN antibody, HBGR1 antibody, MGC133252 antibody, OTTHUMP00000160643 antibody, OTTHUMP00000165781 antibody, OTTHUMP00000224241 antibody, OTTHUMP00000224242 antibody, OTTHUMP00000224243 antibody

    UniProt

    P42261

    途径

    PI3K-Akt Signaling
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