Ataxin 1 抗体 (pSer776)
Quick Overview for Ataxin 1 抗体 (pSer776) (ABIN7138699)
抗原
See all Ataxin 1 (ATXN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer776
-
交叉反应
- 人, 小鼠
-
纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
-
免疫原
- Peptide sequence around phosphorylation site of Serine 776(R-W-S(p)-A-P) derived from Human Ataxin 1.
-
亚型
- IgG
-
-
-
-
应用备注
- WB:1:500-1:1000,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- Ataxin 1 (ATXN1)
-
别名
- ATXN1
-
背景
-
Background: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
Aliases: alternative ataxin1 antibody, Ataxin-1 antibody, ATX1 antibody, ATX1_HUMAN antibody, Atxn1 antibody, D6S504E antibody, OTTHUMP00000016065 antibody, SCA1 antibody, Spinocerebellar ataxia type 1 protein antibody
-
UniProt
- P54253
-
途径
- Synaptic Membrane
抗原
-