PKC theta 抗体 (pSer695)
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北京 101111
Quick Overview for PKC theta 抗体 (pSer695) (ABIN7138681)
抗原
See all PKC theta (PRKCQ) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer695
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原理
- Phospho-PRKCQ (Ser695) Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of serine 695 (N-F-S(p)-F-M) derived from Human PKCth.
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亚型
- IgG
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anti-Protein Kinase C, theta (PRKCQ) (pSer676) antibody
PRKCQ 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 380-634) antibodyPRKCQ 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 15-294) antibodyPRKCQ 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (pThr538) antibodyPRKCQ 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) antibodyPRKCQ 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4105 unconjugated Recombinant Antibody
anti-Protein Kinase C, theta (PRKCQ) (C-Term) antibodyPRKCQ 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (C-Term), (pSer676) antibodyPRKCQ 适用: 人, 大鼠, 小鼠, Cow, 犬, Pig, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 351-450) antibodyPRKCQ 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) (AA 1-230) antibodyPRKCQ 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, theta (PRKCQ) antibodyPRKCQ 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 1B2 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
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别名
- PRKCQ
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背景
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Background: This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Xu ZB, et al.(2004) J Biol Chem 279:50401-50409
Thebault S, et al. (2004) Mol Immunol 40: 931-942Aliases: KPCT_HUMAN antibody, MGC126514 antibody, MGC141919 antibody, nPKC theta antibody, nPKC-theta antibody, nPKCtheta antibody, OTTHUMP00000043364 antibody, OTTHUMP00000043365 antibody, PKC 0 antibody, PKC0 antibody, Prkcq antibody, PRKCT antibody, Protein kinase C theta antibody, Protein kinase C theta type antibody, Protein Kinase Ctheta antibody
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UniProt
- Q04759
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
抗原
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