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BIM 抗体 (pSer69)

This anti-BIM antibody is a 兔 多克隆 antibody detecting BIM in IHC, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7138680
发货至: 中国

Quick Overview for BIM 抗体 (pSer69) (ABIN7138680)

抗原

See all BIM (BCL2L11) 抗体
BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

适用

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宿主

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克隆类型

  • 93
  • 28
多克隆

标记

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This BIM antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
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    pSer69

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of serine 69 (P-A-S(p)-P-G) derived from Human BIM.

    亚型

    IgG
  • 应用备注

    IHC:1:50-1:100, IF:1:100-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

    别名

    BCL2L11

    背景

    Background: Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis

    Fukazawa H, et al. (2004) Mol Cancer Ther , 3(10): 1281-1288
    Luciano F, et al. (2003) Oncogene , 22(43): 6785-6793

    Aliases: BCL2 like 11 antibody, B2L11_HUMAN antibody, BAM antibody, Bcl 2 interacting protein Bim antibody, Bcl 2 related ovarian death agonist antibody, Bcl-2-like protein 11 antibody, BCL2 interacting mediator of cell death antibody, BCL2 like 11 (apoptosis facilitator) antibody, BCL2 like protein 11 antibody, Bcl2-interacting mediator of cell death antibody, Bcl2-L-11 antibody, Bcl2l11 antibody, BIM alpha6 antibody, BIM antibody, BIM beta6 antibody, BIM beta7 antibody, BimEL antibody, BimL antibody, BOD antibody

    UniProt

    O43521

    途径

    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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