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MDC1 抗体 (pSer513)

This 兔 多克隆 antibody specifically detects MDC1 in ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7138640
发货至: 中国
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Quick Overview for MDC1 抗体 (pSer513) (ABIN7138640)

抗原

See all MDC1 抗体
MDC1 (Mdc1 (MDC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This MDC1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    pSer513

    原理

    Phospho-MDC1 (Ser513) Antibody

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from Human MDC1.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MDC1 (Mdc1 (MDC1))

    别名

    MDC1

    背景

    Background:

    The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.

    Nagase T., DNA Res. 3:17-24(1996).
    Shiina T., Genetics 173:1555-1570(2006).
    Mungall A.J., Nature 425:805-811(2003).

    Aliases: Homologue to Drosophila photoreceptor protein calphotin antibody, MDC 1 antibody, Mdc1 antibody, MDC1_HUMAN antibody, Mediation of DNA damage checkpoint 1 antibody, Mediator of DNA damage checkpoint 1 antibody, Mediator of DNA damage checkpoint protein 1 antibody, NFBD 1 antibody, NFBD1 antibody, Nuclear factor with BRCT domains 1 antibody, Nuclear Factor with BRCT Domains Protein 1 antibody

    UniProt

    Q14676
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