CCR5 抗体 (pSer349)
Quick Overview for CCR5 抗体 (pSer349) (ABIN7138569)
抗原
See all CCR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer349
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交叉反应
- 人
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5.
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亚型
- IgG
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应用备注
- WB:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
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别名
- CCR5
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背景
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Background:
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
Martin Oppermann, J. Biol. Chem., Mar 1999, 274: 8875.
Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003, 278: 2190 - 2198.
Ramtin Rahbar, J. Virol., Jul 2006, 80: 7245 - 7259.
H Olbrich, J. Leukoc. Biol., Mar 1999, 65: 281.Aliases: AM4 7 antibody, C C chemokine receptor type 5 antibody, C C CKR 5 antibody, C-C chemokine receptor type 5 antibody, C-C CKR-5 antibody, C-C motif chemokine receptor 5 A159A antibody, CC Chemokine Receptor 5 antibody, CC Chemokine Receptor Type 5 antibody, CC CKR 5 antibody, CC-CKR-5 antibody, CCCKR 5 antibody, CCCKR5 antibody, CCR 5 antibody, CCR-5 antibody, CCR5 antibody, CCR5 chemokine (C C motif) receptor 5 antibody, CCR5_HUMAN antibody, CD 195 antibody, CD195 antibody, CD195 Antigen antibody, Chemokine C C motif receptor 5 antibody, Chemokine receptor CCR5 antibody, CHEMR13 antibody, CKR 5 antibody, CKR5 antibody, CMKBR 5 antibody, CMKBR5 antibody, FLJ78003 antibody, HIV 1 Fusion Coreceptor antibody, HIV-1 fusion coreceptor antibody, HIV1 fusion coreceptor antibody, IDDM22 antibody, MIP-1 alpha receptor antibody
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UniProt
- P51681
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
抗原
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