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CCR5 抗体 (pSer349)

The 兔 多克隆 anti-CCR5 antibody is suitable to detect CCR5 in samples from 人. It has been validated for WB 和 ELISA.
产品编号 ABIN7138569
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for CCR5 抗体 (pSer349) (ABIN7138569)

抗原

See all CCR5 抗体
CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

适用

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宿主

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克隆类型

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多克隆

标记

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This CCR5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    pSer349

    原理

    Phospho-CCR5 (Ser349) Antibody

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

    别名

    CCR5

    背景

    Background:

    Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.

    Martin Oppermann, J. Biol. Chem., Mar 1999, 274: 8875.
    Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003, 278: 2190 - 2198.
    Ramtin Rahbar, J. Virol., Jul 2006, 80: 7245 - 7259.
    H Olbrich, J. Leukoc. Biol., Mar 1999, 65: 281.

    Aliases: AM4 7 antibody, C C chemokine receptor type 5 antibody, C C CKR 5 antibody, C-C chemokine receptor type 5 antibody, C-C CKR-5 antibody, C-C motif chemokine receptor 5 A159A antibody, CC Chemokine Receptor 5 antibody, CC Chemokine Receptor Type 5 antibody, CC CKR 5 antibody, CC-CKR-5 antibody, CCCKR 5 antibody, CCCKR5 antibody, CCR 5 antibody, CCR-5 antibody, CCR5 antibody, CCR5 chemokine (C C motif) receptor 5 antibody, CCR5_HUMAN antibody, CD 195 antibody, CD195 antibody, CD195 Antigen antibody, Chemokine C C motif receptor 5 antibody, Chemokine receptor CCR5 antibody, CHEMR13 antibody, CKR 5 antibody, CKR5 antibody, CMKBR 5 antibody, CMKBR5 antibody, FLJ78003 antibody, HIV 1 Fusion Coreceptor antibody, HIV-1 fusion coreceptor antibody, HIV1 fusion coreceptor antibody, IDDM22 antibody, MIP-1 alpha receptor antibody

    UniProt

    P51681

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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