SUFUH 抗体 (pSer342)
Quick Overview for SUFUH 抗体 (pSer342) (ABIN7138564)
抗原
See all SUFUH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer342
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交叉反应
- 人
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- Peptide sequence around phosphorylation site of Serine 342 (A-P-S(p)-R-K) derived from Human Sufu.
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亚型
- IgG
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应用备注
- WB:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SUFUH (Suppressor of Fused Homolog (SUFUH))
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别名
- SUFU
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背景
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Background: SUFU encodes a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700)
Zimmern P,et al.(2010) Neurourol Urodyn.29(5):715-8.
Wang C,et al. (2010) Development. 137(12):2001-9.
Rabasseda X.et al.(2010) Drug News Perspect.23(4):273-5.Aliases: OTTHUMP00000020374 antibody, OTTHUMP00000020377 antibody, OTTHUMP00000020379 antibody, PRO1280 antibody, SU FU antibody, SU(F)U antibody, Su(fu) antibody, SUFU antibody, SUFU negative regulator of hedgehog signaling antibody, SUFU_HUMAN antibody, SUFUH antibody, SUFUXL antibody, Suppressor of Fused antibody, Suppressor of fused homolog (Drosophila) antibody, Suppressor of fused homolog antibody
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UniProt
- Q9UMX1
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途径
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
抗原
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