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ILK 抗体 (pSer246)

The 兔 多克隆 anti-ILK antibody is suitable to detect ILK in samples from 人. It has been validated for ELISA 和 IHC.
产品编号 ABIN7138506
发货至: 中国
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Quick Overview for ILK 抗体 (pSer246) (ABIN7138506)

抗原

See all ILK 抗体
ILK (Integrin-Linked Kinase (ILK))

适用

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宿主

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克隆类型

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多克隆

标记

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This ILK antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
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    pSer246

    原理

    Phospho-ILK (Ser246) Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Serine 246(I-F-S(p)-H-P) derived from Human ILK.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ILK (Integrin-Linked Kinase (ILK))

    别名

    ILK

    背景

    Background:

    Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

    Hannigan G.E., Nature 379:91-96(1996).
    Janji B., Oncogene 19:3069-3077(2000).
    Tadic B., Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.

    Aliases: 59 kDa serine/threonine protein kinase antibody, 59 kDa serine/threonine-protein kinase antibody, DKFZp686F1765 antibody, Epididymis secretory protein Li 28 antibody, HEL S 28 antibody, ILK 1 antibody, ILK 2 antibody, ILK antibody, ILK-1 antibody, ILK-2 antibody, ILK_HUMAN antibody, ILK1 antibody, ILK2 antibody, Integrin linked kinase 2 antibody, Integrin linked Kinase antibody, Integrin linked protein kinase antibody, Integrin-linked protein kinase antibody, p59 antibody, p59ILK antibody

    UniProt

    Q13418

    途径

    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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