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Vitamin D Receptor 抗体 (pSer208)

VDR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138475
发货至: 中国
  • 抗原 See all Vitamin D Receptor (VDR) 抗体
    Vitamin D Receptor (VDR)
    抗原表位
    • 15
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    • 3
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    pSer208
    适用
    • 96
    • 60
    • 44
    • 2
    • 1
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    • 1
    • 1
    • 1
    宿主
    • 105
    • 13
    • 1
    • 1
    克隆类型
    • 96
    • 24
    多克隆
    标记
    • 65
    • 6
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    • 3
    • 3
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    This Vitamin D Receptor antibody is un-conjugated
    应用范围
    • 94
    • 33
    • 26
    • 26
    • 22
    • 13
    • 13
    • 11
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    • 10
    • 6
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    Western Blotting (WB), ELISA
    交叉反应
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of serine 208 (A-L-S(p)-P-V) derived from Human Vitamin D Receptor.
    亚型
    IgG
    Top Product
    Discover our top product VDR Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Vitamin D Receptor (VDR)
    别名
    VDR (VDR 产品)
    物质类
    Chemical
    背景

    Background:

    Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

    Arriagada G, et al. (2007) J Steroid Biochem Mol Biol 103, 425-9. Jurutka PW, et al. (1996)Proc Natl Acad Sci U S A 93, 3519-24. Jurutka PW, et al. (1993)J Biol Chem 268, 6791-9.

    Aliases: 1 25 dihydroxyvitamin D3 receptor antibody, 1 antibody, 1,25 dihydroxyvitamin D3 receptor antibody, 1,25-@dihydroxyvitamin D3 receptor antibody, 25-dihydroxyvitamin D3 receptor antibody, Member 1 antibody, NR1I1 antibody, Nuclear receptor subfamily 1 group I member 1 antibody, PPP1R163 antibody, Protein phosphatase 1, regulatory subunit 163 antibody, VDR antibody, VDR_HUMAN antibody, Vitamin D (1,25- dihydroxyvitamin D3) receptor antibody, Vitamin D hormone receptor antibody, Vitamin D nuclear receptor variant 1 antibody, Vitamin D receptor antibody, Vitamin D3 receptor antibody

    UniProt
    P11473
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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