TWIST1 抗体
Quick Overview for TWIST1 抗体 (ABIN7138095)
抗原
See all TWIST1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- Peptide sequence around aa.18~22(S-N-S-E-E) derived from Human Twist1
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亚型
- IgG
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anti-Twist Homolog 1 (Drosophila) (TWIST1) (AA 100-202) antibody
TWIST1 适用: 人 WB, ELISA, IP, RNAi 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-Twist Homolog 1 (Drosophila) (TWIST1) (AA 9-74) antibodyTWIST1 适用: 人, 小鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 10E4E6 unconjugated
anti-Twist Homolog 1 (Drosophila) (TWIST1) (AA 9-74) antibodyTWIST1 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Twist Homolog 1 (Drosophila) (TWIST1) (AA 100-202) antibodyTWIST1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-Twist Homolog 1 (Drosophila) (TWIST1) (AA 106-174) antibodyTWIST1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2G12 unconjugated
anti-Twist Homolog 1 (Drosophila) (TWIST1) (AA 1-100) antibodyTWIST1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Twist Homolog 1 (Drosophila) (TWIST1) (Center) antibodyTWIST1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Twist Homolog 1 (Drosophila) (TWIST1) (AA 9-74) antibodyTWIST1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2F8E7 unconjugated
anti-Twist Homolog 1 (Drosophila) (TWIST1) antibodyTWIST1 适用: 人 WB, ICC, FACS, DB 宿主: 小鼠 Monoclonal Twist2C1a unconjugated
anti-Twist Homolog 1 (Drosophila) (TWIST1) antibodyTWIST1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB:1:500-1:1000, IHC:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))
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别名
- TWIST1
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背景
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Background:
Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation.
"Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity."Sosic D., Richardson J.A., Yu K., Ornitz D.M., Olson E.N.Cell 112:169-180(2003)
"Mutations of the TWIST gene in the Saethre-Chotzen syndrome."el Ghouzzi V., le Merrer M., Perrin-Schmitt F., et al., Nat. Genet. 15:42-46(1997)Aliases: ACS3 antibody; B-HLH DNA binding protein antibody; bHLHa38 antibody; BPES2 antibody; BPES3 antibody; Class A basic helix-loop-helix protein 38 antibody; CRS antibody; CRS1 antibody; CSO antibody; H-twist antibody; OTTHUMP00000116043 antibody; SCS antibody; Twist basic helix loop helix transcription factor 1 antibody; Twist family bHLH transcription factor 1 antibody; Twist homolog 1 (Drosophila) antibody; Twist homolog 1 antibody; TWIST homolog of drosophila antibody; Twist related protein 1 antibody; Twist-related protein 1 antibody; TWIST1 antibody; TWST1_HUMAN antibody
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UniProt
- Q15672
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途径
- p53 Pathway, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity
抗原
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