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GRIPAP1 抗体 (AA 814-818)

This anti-GRIPAP1 antibody is a 兔 多克隆 antibody detecting GRIPAP1 in WB 和 ELISA. Suitable for 大鼠.
产品编号 ABIN7138016
发货至: 中国

Quick Overview for GRIPAP1 抗体 (AA 814-818) (ABIN7138016)

抗原

See all GRIPAP1 抗体
GRIPAP1 (GRIP1 Associated Protein 1 (GRIPAP1))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This GRIPAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 814-818

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide

    免疫原

    Peptide sequence around aa. 814-818(Q-E-I-V-R ) derived from Rat GRASP.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    GRIPAP1 (GRIP1 Associated Protein 1 (GRIPAP1))

    别名

    Gripap1

    背景

    Background: GRASP (GRP1-associated scaffold protein, tamalin) is a 395 amino acid proteinencoded by the human gene GRASP . GRASP is a scaffold protein that com-prises multiple protein-interacting domains, including a 95 kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipperregion and a carboxyl-terminal PDZ-binding motif. GRASP is involved with intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. GRASP forms a heteromer composed of GRASP , PSCD2 and at least one mGluR-1. It also interacts with PSCD3, mGluR-2, mGluR-3 and mGluR-5. GRASP is highly expressed in brain and has lower levels of expression in lung, heart, embryo, kidney and ovary.

    Kitano, J., Kimura, K., Yamazaki, Y., Soda, T., Shigemoto, R., Nakajima, Y.and Nakanishi, S. 2002. Tamalin, J. Neurosci. 22: 280-1289.
    Hall, B.S., Gabernet-Castello, C., Voak, A., Goulding, D., Natesan, S.K. and Field, M.C. 2006. J. Biol. Chem. 281: 27600-27612.
    Sugi, T., Oyama, T., Muto, T., Nakanishi, S., Morikawa, K. and Jingami, H. 2007. Crystal structures of autoinhibitory PDZ domain of Tamalin EMBO J.26: 2192-2205.

    Aliases: Gripap1 antibody, Grasp1GRIP1-associated protein 1 antibody, GRASP-1) [Cleaved into: GRASP-1 C-terminal chain antibody, 30 kDa C-terminus form)] antibody

    UniProt

    Q9JHZ4

    途径

    SARS-CoV-2 Protein Interactome
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