HMGCR 抗体 (AA 251-350)
Quick Overview for HMGCR 抗体 (AA 251-350) (ABIN709196)
抗原
See all HMGCR 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 251-350
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Dog,Cow,Pig,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human HMGCR
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
-
: "Ethanol extract of Pinus koraiensis leaves containing lambertianic acid exerts anti-obesity and hypolipidemic effects by activating adenosine monophosphate-activated protein kinase (AMPK)." in: BMC complementary and alternative medicine, Vol. 16, pp. 51, (2016) (PubMed).
: "Effects of SIRT1 gene knock-out via activation of SREBP2 protein-mediated PI3K/AKT signaling on osteoarthritis in mice." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 36, Issue 5, pp. 683-690, (2016) (PubMed).
: "Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters." in: Life sciences, Vol. 151, pp. 50-60, (2016) (PubMed).
: "The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 21, Issue 11, pp. 1373-81, (2014) (PubMed).
-
: "Ethanol extract of Pinus koraiensis leaves containing lambertianic acid exerts anti-obesity and hypolipidemic effects by activating adenosine monophosphate-activated protein kinase (AMPK)." in: BMC complementary and alternative medicine, Vol. 16, pp. 51, (2016) (PubMed).
-
- HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))
-
别名
- HMGCR
-
背景
-
Synonyms: LDLCQ3, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase, HMGCR
Background: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
-
基因ID
- 3156
-
UniProt
- P04035
-
途径
- AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
抗原
-