MGEA5 抗体
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北京 101111
Quick Overview for MGEA5 抗体 (ABIN7130225)
抗原
See all MGEA5 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MGEA5 Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of Human MGEA5
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
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别名
- MGEA5
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背景
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Background: The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT, which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications. Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3. Shows highest expression in the brain, placenta and pancreas.
Aliases: Beta-hexosaminidase antibody, Beta-N-acetylglucosaminidase antibody, Beta-N-acetylhexosaminidase antibody, Bifunctional protein NCOAT antibody, HEXC antibody, Hyaluronidase in meningioma antibody, KIAA0679 antibody, MEA5 antibody, Meningioma expressed antigen 5 antibody, Meningioma-expressed antigen 5 antibody, MGEA 5 antibody, Mgea5 antibody, N-acetyl-beta-D-glucosaminidase antibody, N-acetyl-beta-glucosaminidase antibody, NCOAT antibody, Nuclear cytoplasmic O GlcNAcase and acetyltransferase antibody, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase antibody, OGA antibody, OGA_HUMAN antibody, Protein O-GlcNAcase antibody
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UniProt
- O60502
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途径
- Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
抗原
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