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Recombinant NKX2-1 抗体

This anti-NKX2-1 antibody is a 兔 单克隆 antibody detecting NKX2-1 in WB, IHC, FACS 和 ELISA. Suitable for 人.
产品编号 ABIN7127859
发货至: 中国

Quick Overview for Recombinant NKX2-1 抗体 (ABIN7127859)

抗原

See all NKX2-1 抗体
NKX2-1 (NK2 Homeobox 1 (NKX2-1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This NKX2-1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

克隆位点

6C11
  • 交叉反应

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human TTF1

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, FC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    NKX2-1 (NK2 Homeobox 1 (NKX2-1))

    别名

    NKX2-1

    背景

    Background: Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).

    Aliases: Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1) (Thyroid-specific enhancer-binding protein) (T/EBP), NKX2-1, NKX2A TITF1 TTF1

    UniProt

    P43699

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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