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Recombinant SSTR2 抗体

SSTR2 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 1C3 unconjugated Recombinant Antibody
产品编号 ABIN7127820
发货至: 中国
  • 抗原 See all SSTR2 抗体
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    抗体类型
    Recombinant Antibody
    适用
    • 45
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    宿主
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    克隆类型
    • 41
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    单克隆
    标记
    • 35
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    This SSTR2 antibody is un-conjugated
    应用范围
    • 22
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    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human Somatostatin Receptor 2
    克隆位点
    1C3
    亚型
    IgG
    Top Product
    Discover our top product SSTR2 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    别名
    SSTR2 (SSTR2 产品)
    别名
    Smstr2 antibody, SSTR-2 antibody, Smstr-2 antibody, sst2 antibody, SS2R antibody, SSTR2 antibody, MGC80373 antibody, somatostatin receptor 2 antibody, somatostatin receptor 2 L homeolog antibody, SSTR2 antibody, Sstr2 antibody, sstr2.L antibody
    背景

    Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

    Aliases: Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1), SSTR2

    UniProt
    P30874
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