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Recombinant Menin 抗体

This anti-Menin antibody is a 兔 单克隆 antibody detecting Menin in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7127614
发货至: 中国

Quick Overview for Recombinant Menin 抗体 (ABIN7127614)

抗原

See all Menin (MEN1) 抗体
Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

抗体类型

Recombinant Antibody

适用

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宿主

  • 84
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克隆类型

  • 79
  • 16
单克隆

标记

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This Menin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

8G11
  • 原理

    MEN1 Recombinant Monoclonal Antibody

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Menin

    亚型

    IgG
  • 应用备注

    WB:1:500-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

    别名

    MEN1

    背景

    Background: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

    Aliases: Menin, MEN1, SCG2

    UniProt

    O00255

    途径

    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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