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Recombinant IDO1 抗体

This anti-IDO1 antibody is a 兔 单克隆 antibody detecting IDO1 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7127573
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant IDO1 抗体 (ABIN7127573)

抗原

See all IDO1 抗体
IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

抗体类型

Recombinant Antibody

适用

  • 87
  • 32
  • 16
  • 9
  • 1
  • 1
  • 1

宿主

  • 80
  • 14
  • 2
  • 1

克隆类型

  • 68
  • 29
  • 1
单克隆

标记

  • 60
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This IDO1 antibody is un-conjugated

应用范围

  • 80
  • 34
  • 28
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  • 22
  • 21
  • 17
  • 15
  • 14
  • 9
  • 6
  • 2
  • 2
  • 1
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  • 1
ELISA, Immunohistochemistry (IHC)

克隆位点

9E5
  • 原理

    IDO1 Recombinant Monoclonal Antibody

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human INDO

    亚型

    IgG
  • 应用备注

    IHC:1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

    别名

    IDO1

    背景

    Background: Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses (PubMed:25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells (PubMed:25691885). Acts as a suppressor of anti-tumor immunity (PubMed:23103127, PubMed:25157255, PubMed:14502282, PubMed:25691885). Limits the growth of intracellular pathogens by depriving tryptophan (PubMed:25691885). Protects the fetus from maternal immune rejection (PubMed:25691885).

    Aliases: Indoleamine 2,3-dioxygenase 1 (IDO-1) (EC 1.13.11.52) (Indoleamine-pyrrole 2,3-dioxygenase), IDO1, IDO INDO

    UniProt

    P14902

    途径

    Activated T Cell Proliferation
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