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Recombinant ILK 抗体

This anti-ILK antibody is a 兔 单克隆 antibody detecting ILK in WB, ELISA, IP 和 IF. Suitable for 人.
产品编号 ABIN7127572
发货至: 中国

Quick Overview for Recombinant ILK 抗体 (ABIN7127572)

抗原

See all ILK 抗体
ILK (Integrin-Linked Kinase (ILK))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This ILK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

克隆位点

6A5
  • 交叉反应

    人, 小鼠

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human ILK

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200, IP:1:200-1:1000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ILK (Integrin-Linked Kinase (ILK))

    别名

    ILK

    背景

    Background: Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715). May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715).

    Aliases: Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (ILK-1) (ILK-2) (p59ILK), ILK, ILK1 ILK2

    UniProt

    Q13418

    途径

    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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