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Recombinant GZMB 抗体

This anti-GZMB antibody is a 兔 单克隆 antibody detecting GZMB in IHC, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7127523
发货至: 中国

Quick Overview for Recombinant GZMB 抗体 (ABIN7127523)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

抗体类型

Recombinant Antibody

适用

  • 178
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宿主

  • 95
  • 91
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克隆类型

  • 101
  • 87
单克隆

标记

  • 101
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This GZMB antibody is un-conjugated

应用范围

  • 92
  • 82
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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

克隆位点

6A1
  • 交叉反应

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Granzyme B

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    GZMB

    背景

    Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    Aliases: Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E), GZMB, CGL1 CSPB CTLA1 GRB

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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