Recombinant FOXO3 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant FOXO3 抗体 (ABIN7127500)
抗原
See all FOXO3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- FOXO3 Recombinant Monoclonal Antibody
-
纯化方法
- Affinity-chromatography
-
免疫原
- A synthesized peptide derived from human FOXO3
-
亚型
- IgG
-
-
anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyVerified FOXO3 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibodyFOXO3 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyKO Validated FOXO3 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 224-253) antibodyFOXO3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer253) antibodyFOXO3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- FOXO3 (Forkhead Box O3 (FOXO3))
-
别名
- FOXO3
-
背景
-
Background: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress (PubMed:10102273, PubMed:16751106). Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' (PubMed:21329882). Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation (PubMed:21329882). In response to metabolic stress, translocates into the mitochondria where it promotes mtDNA transcription (PubMed:23283301).
Aliases: Forkhead box protein O3, AF6q21 protein, FOXO3
-
UniProt
- O43524
-
途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
抗原
-
