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Recombinant DKK1 抗体

This anti-DKK1 antibody is a 兔 单克隆 antibody detecting DKK1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7127455
发货至: 中国

Quick Overview for Recombinant DKK1 抗体 (ABIN7127455)

抗原

See all DKK1 抗体
DKK1 (Dickkopf Homolog 1 (DKK1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This DKK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

1D12
  • 交叉反应

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human DKK1

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DKK1 (Dickkopf Homolog 1 (DKK1))

    别名

    DKK1

    背景

    Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:22000856). DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (PubMed:17143291). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (By similarity).

    Aliases: Dickkopf-related protein 1 (Dickkopf-1) (Dkk-1) (hDkk-1) (SK), DKK1

    UniProt

    O94907

    途径

    WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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