Recombinant DKK1 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant DKK1 抗体 (ABIN7127455)
抗原
See all DKK1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- DKK1 Recombinant Monoclonal Antibody
-
纯化方法
- Affinity-chromatography
-
免疫原
- A synthesized peptide derived from human DKK1
-
亚型
- IgG
-
-
anti-Dickkopf Homolog 1 (DKK1) (AA 1-266) antibody
DKK1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB52126 unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 1-266) antibodyDKK1 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2A5 unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 33-266) antibodyDKK1 适用: 人 WB 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 81-180) antibodyDKK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C10 unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 201-266) antibodyDKK1 适用: 人, 犬 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 36-260) antibodyDKK1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 33-266) antibodyDKK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 33-266) antibodyDKK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 71-266) antibodyDKK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf Homolog 1 (DKK1) (C-Term) antibodyVerified DKK1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
-
-
应用备注
- WB:1:500-1:5000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- DKK1 (Dickkopf Homolog 1 (DKK1))
-
别名
- DKK1
-
背景
-
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:22000856). DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (PubMed:17143291). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (By similarity).
Aliases: Dickkopf-related protein 1 (Dickkopf-1) (Dkk-1) (hDkk-1) (SK), DKK1
-
UniProt
- O94907
-
途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
-
