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Recombinant Histone H3.3 抗体

This anti-Histone H3.3 antibody is a 兔 单克隆 antibody detecting Histone H3.3 in ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7127296
发货至: 中国

Quick Overview for Recombinant Histone H3.3 抗体 (ABIN7127296)

抗原

See all Histone H3.3 (H3F3A) 抗体
Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Histone H3.3 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

4H2
  • 交叉反应

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:50-1:500, IF:1:30-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

    别名

    H3F3A

    背景

    Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Aliases: Histone H3.3, H3F3A, H3.3A, H3F3, PP781, AND, H3F3B, H3.3B

    UniProt

    P84243
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