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Recombinant MCAM 抗体

This anti-MCAM antibody is a 兔 单克隆 antibody detecting MCAM in IHC, FACS, WB, IF 和 ELISA. Suitable for 人.
产品编号 ABIN7127274
发货至: 中国

Quick Overview for Recombinant MCAM 抗体 (ABIN7127274)

抗原

See all MCAM 抗体
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This MCAM antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), ELISA

克隆位点

8A10
  • 交叉反应

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:30-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    别名

    MCAM

    背景

    Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

    Aliases: Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, CD146, MCAM, MUC18

    UniProt

    P43121
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