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CD33 抗体 (AA 51-224)

This anti-CD33 antibody is a 小鼠单克隆 antibody detecting CD33 in IHC (f). Suitable for 人.

产品编号 ABIN7127193

发货至: 中国

Quick Overview for CD33 抗体 (AA 51-224) (ABIN7127193)

抗原

See all CD33 抗体

CD33

适用

178
35
16
13
7
6
3
1

人

宿主

小鼠

克隆类型

单克隆

标记

This CD33 antibody is un-conjugated

应用范围

118
108
43
41
28
26
26
25
19
18
10
8
6
5
4
2
2
2
1
1
1
1
1
1
1

Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Discover our top product CD33 Primary Antibody

抗原表位
16

16

13

9

8

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 51-224

特异性

Recognizes a 67 kDa glycoprotein, which is identified as CD33. It is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.

交叉反应（详细）

Human.

纯化方法

1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

免疫原

Recombinant fragment (around aa51-224) of human CD33 protein (exact sequence is proprietary)

亚型

IgG2
anti-CD33 (CD33) (AA 101-200) antibody
CD33 适用: 人, 小鼠 FACS, WB, ELISA, IHC (fro), ICC, IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD33 (CD33) (AA 15-237) antibody
CD33 适用: 人 FACS, WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2C6B7 unconjugated

anti-CD33 (CD33) (AA 15-237) antibody
CD33 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 2C6B7 unconjugated

anti-CD33 (CD33) (AA 18-240) antibody
CD33 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD33 (CD33) (AA 49-259) antibody
CD33 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD33 (CD33) (AA 261-364) antibody
CD33 适用: 人 FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD33 (CD33) (AA 1-364) antibody
CD33 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D12-G4 unconjugated

anti-CD33 (CD33) antibody
CD33 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD33 (CD33) antibody
CD33 适用: 人, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, Func, MS 宿主: 小鼠 Monoclonal WM53 unconjugated

anti-CD33 (CD33) antibody
CD33 适用: 人, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, MS 宿主: 小鼠 Monoclonal WM53 unconjugated

应用备注

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human dendritic and mast cells. Human lymph nodes and tonsils.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

Prepared in 10 mM PBS, WITHOUT BSA and Azide.

储存液

Azide free

储存条件

-20 °C,-80 °C

储存方法

Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

有效期

24 months
抗原

CD33

别名

CD33

背景

Gp67, My9, Myeloid cell surface antigen CD33, p67, Sialic acid-binding Ig-like lectin 3 (SIGLEC3),CD33 / SIGLEC3 (Myeloid Cell Surface Antigen)
Cellular localisation: Cell surface

分子量

67kDa

基因ID

945, 83731

UniProt

P20138

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