CD20 抗体
Our Local Distributor
北京 101111
Quick Overview for CD20 抗体 (ABIN7127163)
抗原
See all CD20 (MS4A1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Recognizes a protein of 30-33 kDa, which is identified as CD20 (Workshop V, Code CD20.12. Workshop IV, Code B17). It recognizes an extracellular domain of CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.
-
交叉反应 （详细）
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Stimulated human leukocytes
-
亚型
- IgG3
-
-
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (C-Term) antibody
Verified MS4A1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 213-297) antibodyMS4A1 适用: 人 FACS, WB, IHC, IF, ELISA, StM, Coat 宿主: 小鼠 Monoclonal MS4A1-3409 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 适用: 人 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal L26 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 适用: 人 FACS, IF, IHC (f) 宿主: 小鼠 Monoclonal L26-IGEL-773 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) antibodyMS4A1 适用: 人 FACS, WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 适用: 人 FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal rIGEL-773 unconjugated Recombinant Antibody
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 适用: 人, Cow FACS, IP 宿主: 小鼠 Monoclonal MEM-97 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 适用: 人, Cow FACS, IP 宿主: 小鼠 Monoclonal MEM-97 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) antibodyMS4A1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 210-297) antibodyMS4A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5C11 unconjugated
-
-
应用备注
-
Known_Application: Functional Studies (Order Ab without BSA & Azide); ,ELISA (For coating, order antibody without BSA);,Optimal dilution for a specific application should be determined.
Positive_Control: Daudi, Raji, and U266, and human lymphocytes. Lymph nodes and tonsils.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
-
别名
- MS4A1
-
背景
-
APY, ATOPY, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, Bp35, Fc epsilon receptor I beta chain, Fc Fragment of IgE high affinity I receptor for beta polypeptide, FCER1B, High affinity immunoglobulin epsilon receptor subunit beta, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, LEU16, Leukocyte surface antigen Leu-16, Ly44, Membrane spanning 4 domains subfamily A member 2, Membrane-spanning 4-domains subfamily A member 1 (MS4A1),CD20 / MS4A1 (B-Cell Marker)
Cellular localisation: Predominantly cell surface with some cytoplasmic -
分子量
- 33-37kDa
-
基因ID
- 931, 712553
-
UniProt
- P11836
抗原
-
