Recombinant TSHB 抗体
Quick Overview for Recombinant TSHB 抗体 (ABIN7127026)
抗原
See all TSHB 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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特异性
- The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human TSH beta fragment
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亚型
- IgG1
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anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 20-139) antibody
TSHB 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1D12G1 unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) antibodyTSHB 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) antibodyTSHB 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 21-138) antibodyTSHB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 58-86) antibodyTSHB 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21119 unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 21-138) antibodyTSHB 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 20-138) antibodyTSHB 适用: 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) antibodyTSHB 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal TSHb-1317 unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 51-138) antibodyTSHB 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 小鼠 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) antibodyTSHB 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Normal pituitary or pituitary tumor.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- TSHB (Thyroid Stimulating Hormone, beta (TSHB))
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别名
- TSHB
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背景
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CHNG4, Thyroid stimulating hormone beta subunit, Thyroid stimulating hormone, beta precursor, Thyrotropin beta subunit, TSHB,Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker)
Cellular localisation: Cytoplasmic -
分子量
- 16kDa
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基因ID
- 7252, 406687
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UniProt
- P01222
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途径
- Thyroid Hormone Synthesis, Peptide Hormone Metabolism
抗原
-
