Recombinant SHBG 抗体
Quick Overview for Recombinant SHBG 抗体 (ABIN7126939)
抗原
See all SHBG 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human SHBG protein
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亚型
- IgG1
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应用备注
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Known_Application: ELISA (For coating, order Ab without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human liver, placenta or testis.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- SHBG (Sex Hormone Binding Globulin (SHBG))
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别名
- SHBG
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背景
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Androgen binding protein (ABP), Sex hormone-binding globulin (SHBG), Sex steroid binding protein (SBP), Sex steroid-binding protein, Testis-specific androgen-binding protein, Testosterone binding beta globulin, Testosterone-Estradiol-Binding Globulin (TEBG),Sex Hormone Binding Globulin (SHBG)
Cellular localisation: Cytoplasm. Extracellular (Secreted). -
分子量
- 45kDa
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基因ID
- 6462, 632235
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UniProt
- P04278
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途径
- Hormone Transport
抗原
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