Recombinant SDHB 抗体
Quick Overview for Recombinant SDHB 抗体 (ABIN7126928)
抗原
See all SDHB 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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特异性
- Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a key component of the citric acid cycle and the electron transport chain, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane. Many cancers are generally positive for SDHB, including renal cell carcinomas and gastrointestinal stromal tumors. A subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Synthetic peptide corresponding to residues in human SDHB was used as an immunogen.
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亚型
- IgG
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anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (AA 97-282) antibody
SDHB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (AA 29-280) antibodySDHB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (C-Term) antibodySDHB 适用: 人, 小鼠 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (AA 29-280) antibodySDHB 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2B2B1 unconjugated
anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (Middle Region) antibodySDHB 适用: 人, 小鼠, 大鼠, 斑马鱼, 豚鼠, 兔, Cow, 犬, 马, 山羊, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) antibodySDHB 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Monoclonal 7D12 unconjugated Recombinant Antibody
anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) antibodySDHB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (AA 1-280) antibodySDHB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (AA 29-280) antibodySDHB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (AA 201-280) antibodySDHB 适用: 人 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat or HepG2 cells. Human kidney or heart tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
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别名
- SDHB
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背景
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CWS2, DHSB, Iron-sulfur subunit of complex II, PGL4, SDH2, SDHB, SDHIP, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein,SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)
Cellular localisation: Cytoplasm. Mitochondria. -
分子量
- 32kDa
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基因ID
- 6390, 465924
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UniProt
- P21912
抗原
-
