Recombinant RRM1 抗体 (AA 700-800)
Quick Overview for Recombinant RRM1 抗体 (AA 700-800) (ABIN7126906)
抗原
See all RRM1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 700-800
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特异性
- Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Synthetic peptide corresponding to residues within aa700-800 of human RRM1 (exact sequence is proprietary)
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亚型
- IgG
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anti-Ribonucleotide Reductase M1 (RRM1) (AA 593-792) antibody
RRM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 541-792) antibodyRRM1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2D6D8 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 1-213) antibodyRRM1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (Center) antibodyRRM1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 593-792) antibodyRRM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 541-792) antibodyRRM1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5G5 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 733-778) antibodyRRM1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) antibodyRRM1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (Internal Region) antibodyRRM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) antibodyRRM1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 3D6H5 unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human breast, lung or colon carcinoma tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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别名
- RRM1
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背景
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Ribonucleoside diphosphate reductase large subunit, Ribonucleoside diphosphate reductase M1 chain, RR1, RRM1, RIR1, Ribonucleotide reductase M1 polypeptide, Ribonucleotide reductase R1 subunit,Ribonucleotide Reductase M1 / RRM1
Cellular localisation: Cytoplasm -
分子量
- 94kDa
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基因ID
- 6240, 445705
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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