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Recombinant ACE2 抗体 (AA 705-805)

ACE2 适用: 人 ELISA, Coat, IHC (f) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
产品编号 ABIN7126871
发货至: 中国
  • 抗原 See all ACE2 抗体
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 16
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    AA 705-805
    适用
    • 125
    • 54
    • 47
    • 6
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    • 1
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    宿主
    • 113
    • 19
    • 6
    克隆类型
    • 103
    • 35
    单克隆
    标记
    • 72
    • 16
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    This ACE2 antibody is un-conjugated
    应用范围
    • 115
    • 64
    • 50
    • 36
    • 30
    • 19
    • 17
    • 10
    • 10
    • 10
    • 10
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    ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II toangiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage ofangiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment (around aa705-805) of human ACE2 (exact sequence is proprietary)
    亚型
    IgG
    Top Product
    Discover our top product ACE2 Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human kidney, heart, testis or small intestine.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    别名
    ACE2 (ACE2 产品)
    别名
    ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, ACEH antibody, 2010305L05Rik antibody, zgc:92514 antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme 2 antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antibody, ACE antibody, ACE2 antibody, Ace2 antibody, ace2 antibody
    背景
    ACE related carboxypeptidase, ACE2, ACEH, Angiotensin converting enzyme 2, Angiotensin converting enzyme like protein, Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2, Angiotensin-converting enzyme homolog, EC 3.4.17, DKFZP434A014, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2,ACE2 / Angiotensin I Converting Enzyme 2
    Cellular localisation: Cell membrane. Secreted.
    分子量
    92kDa
    基因ID
    59272, 178098
    UniProt
    Q9BYF1
    途径
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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