PTGS2 抗体 (AA 442-572)
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- 抗原 See all PTGS2 抗体
- PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
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抗原表位
- AA 442-572
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PTGS2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general housekeeping functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs. COX2 expression is significantly increased in 85-90 % of human colorectal adenocarcinomas whereas levels of COX-1 are not changed.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human COX2 protein fragment (around aa 442-572) (exact sequence is proprietary)
- 亚型
- IgG2a
- Top Product
- Discover our top product PTGS2 Primary Antibody
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anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) (AA 501-604) antibody
PTGS2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) (AA 375-604) antibodyPTGS2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) (C-Term) antibodyVerified PTGS2 适用: 人, 小鼠 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) (AA 363-391) antibodyPTGS2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17409 unconjugated
anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) (AA 301-400) antibodyPTGS2 适用: 人, 小鼠, 大鼠, 绵羊 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) (AA 1-604) antibodyPTGS2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) (AA 555-604) antibodyPTGS2 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) (C-Term) antibodyPTGS2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) (C-Term) antibodyPTGS2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) antibodyPTGS2 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 10B2 unconjugated Recombinant Antibody
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human colon or lung carcinoma. HepG2 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
- 别名
- PTGS2 (PTGS2 产品)
- 背景
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Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase, GRIPGHS, Macrophage activation-associated marker protein P71/73, PES-2, PGG/HS, PGHS-2, Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Prostaglandin endoperoxide synthase 2, PTGS2, TIS10,Cycloxygenase-2 (COX-2)
Cellular localisation: Cytoplasm. - 分子量
- 70-72kDa
- 基因ID
- 5743, 196384
- UniProt
- P35354
- 途径
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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