NEUROD2 抗体
Quick Overview for NEUROD2 抗体 (ABIN7126743)
抗原
See all NEUROD2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (i²2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human NEUROD2 protein
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亚型
- IgG2b
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anti-Neurogenic Differentiation 2 (NEUROD2) (Internal Region) antibody
NEUROD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (AA 1-382) antibodyNEUROD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (AA 266-375) antibodyNEUROD2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (AA 1-382) antibodyNEUROD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (AA 71-120) antibodyNEUROD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (C-Term) antibodyNEUROD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (Internal Region) antibodyNEUROD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (Center) antibodyNEUROD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells. Human brain.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))
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别名
- NEUROD2
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背景
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BHLHa1, class A basic helix loop helix protein 1, NDR2, NDRF, NeuroD-related factor, NeuroD2, neurogenic basic helix loop helix protein, neurogenic differentiation 2, Neurogenic differentiation factor 2, neuronal differentiation 2,NEUROD2 (Neurogenic Differentiation 2) (Transcription Factor)
Cellular localisation: Nucleus. -
分子量
- 41kDa
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基因ID
- 4761, 322431
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UniProt
- Q15784
抗原
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