Recombinant LHB 抗体
Quick Overview for Recombinant LHB 抗体 (ABIN7126643)
抗原
See all LHB 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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特异性
 - LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor, however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
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交叉反应 (详细)
 - Human.
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纯化方法
 - 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
 - Recombinant full-length human LHB protein
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亚型
 - IgG
 
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Anterior Pituitary
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限制
 - 仅限研究用
 
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浓度
 - 1.0 mg/mL
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缓冲液
 - Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
 - Azide free
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储存条件
 - -20 °C,-80 °C
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储存方法
 - Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
 - 24 months
 
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- LHB (Luteinizing Hormone beta Polypeptide (LHB))
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别名
 - LHB
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物质类
 - Hormone
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背景
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                        Chorionic Gonadotropin, Beta polypeptide 4 (CGB4), hLHB, Interstitial cell stimulating hormone beta chain, Leutropin, LH-B, LHB, LSH-B, LSH-beta, Luteinizing hormone beta polypeptide, Lutropin beta chain,LH-beta (Luteinizing Hormone-beta)
Cellular localisation: Cytoplasm. Secreted. - 
                                            
分子量
 - 22kDa
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基因ID
 - 3972, 154704
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UniProt
 - P01229
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途径
 - Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
 
抗原
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