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Recombinant LHB 抗体

This anti-LHB antibody is a 小鼠 单克隆 antibody detecting LHB in IHC (f). Suitable for 人.
产品编号 ABIN7126642
发货至: 中国

Quick Overview for Recombinant LHB 抗体 (ABIN7126642)

抗原

See all LHB 抗体
LHB (Luteinizing Hormone beta Polypeptide (LHB))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This LHB antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 特异性

    LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor, however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human LHB protein

    亚型

    IgG1
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Anterior Pituitary

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    LHB (Luteinizing Hormone beta Polypeptide (LHB))

    别名

    LHB

    物质类

    Hormone

    背景

    ChorionicGonadotropin, Betapolypeptide 4 (CGB4), hLHB, Interstitial cell stimulating hormone beta chain, Leutropin, LH-B, LHB, LSH-B, LSH-beta, Luteinizing hormone beta polypeptide, Lutropin beta chain,LH-beta (Luteinizing Hormone-beta)
    Cellular localisation: Cytoplasm.Secreted.

    分子量

    22kDa

    基因ID

    3972, 154704

    UniProt

    P01229

    途径

    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
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