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Recombinant Galectin 3 抗体 (AA 150-200)

The 兔 单克隆 anti-Galectin 3 antibody is suitable to detect Galectin 3 in samples from 人. It has been validated for IHC (f).
产品编号 ABIN7126641
发货至: 中国
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Quick Overview for Recombinant Galectin 3 抗体 (AA 150-200) (ABIN7126641)

抗原

See all Galectin 3 (LGALS3) 抗体
Galectin 3 (LGALS3)

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This Galectin 3 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

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    AA 150-200

    特异性

    Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid.Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiationof benign and malignant thyroid neoplasms.Galectin-3 may also be useful in the identification of certain liver disorders.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    A synthetic peptide from the C-terminus of human LGALS3protein (aa 150-200) (exact sequence is proprietary)

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human papillary thyroid carcinoma tissue.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Galectin 3 (LGALS3)

    别名

    LGALS3

    物质类

    Chemical

    背景

    35 kDa lectin, Carbohydrate-binding protein 35, CBP35, Gal-3, GAL3, Galactose-specific lectin 3, GALBP, Galectin-3, GALIG, GBP, IgE-binding protein, L-34 galactoside-binding lectin, L31, Laminin-binding protein, Lectin L-29, Lectin, galactose binding, soluble 3, LGALS2, LGALS3, MAC2, Macrophage galactose-specific lectin,Galectin-3 (LGALS3) (Thyroid Cell Marker)
    Cellular localisation: Cytoplasm

    分子量

    26kDa

    基因ID

    3958, 531081

    UniProt

    P17931

    途径

    RTK signaling
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