Galectin 3 抗体 (AA 150-200)
Quick Overview for Galectin 3 抗体 (AA 150-200) (ABIN7126640)
抗原
See all Galectin 3 (LGALS3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-200
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特异性
- Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid.Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiationof benign and malignant thyroid neoplasms.Galectin-3 may also be useful in the identification of certain liver disorders.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- A synthetic peptide from the C-terminus of human LGALS3protein (aa 150-200) (exact sequence is proprietary)
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亚型
- IgG1
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human papillary thyroid carcinoma tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Galectin 3 (LGALS3)
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别名
- LGALS3
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物质类
- Chemical
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背景
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35 kDa lectin, Carbohydrate-binding protein 35, CBP35, Gal-3, GAL3, Galactose-specific lectin 3, GALBP, Galectin-3, GALIG, GBP, IgE-binding protein, L-34 galactoside-binding lectin, L31, Laminin-binding protein, Lectin L-29, Lectin, galactose binding, soluble 3, LGALS2, LGALS3, MAC2, Macrophage galactose-specific lectin,Galectin-3 (LGALS3) (Thyroid Cell Marker)
Cellular localisation: Cytoplasm. -
分子量
- 30kDa
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基因ID
- 3958, 531081
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UniProt
- P17931
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途径
- RTK signaling
抗原
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