Recombinant RPSA/Laminin Receptor 抗体
Quick Overview for Recombinant RPSA/Laminin Receptor 抗体 (ABIN7126637)
抗原
See all RPSA/Laminin Receptor (RPSA) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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特异性
 - Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.
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交叉反应 (详细)
 - Human.
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纯化方法
 - 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
 - Recombinant full-length human RPSA protein
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亚型
 - IgG
 
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human breast, colon or ovarian carcinoma.
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限制
 - 仅限研究用
 
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浓度
 - 1.0 mg/mL
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缓冲液
 - Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
 - Azide free
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储存条件
 - -20 °C,-80 °C
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储存方法
 - Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
 - 24 months
 
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- RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
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别名
 - RPSA
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背景
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                        34/67 kDa Laminin Receptor, 37 kDa Laminin Receptor precursor, 37/67 kDa Laminin Receptor, 37LRP, 40S Ribosomal Protein SA, 67 kDa Laminin Receptor, 67LR, Colon Carcinoma Laminin-binding Protein, LAMBR, Laminin receptor 1, Laminin-binding Protein precursor p40, LAMR1, LBP/p40, LRP/LR, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, Ribosomal Protein SA (RPSA),Laminin Receptor/ RPSA (Marker of Metastatic Potential)
Cellular localisation: Cell Surface,Cytoplasmic and Nuclear - 
                                            
分子量
 - 37-67kDa
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基因ID
 - 3921, 449909
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UniProt
 - P08865
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途径
 - Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
 
抗原
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