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Recombinant Cytokeratin 7 抗体 (AA 1-100)

This anti-Cytokeratin 7 antibody is a 兔 单克隆 antibody detecting Cytokeratin 7 in IHC (f). Suitable for 人.
产品编号 ABIN7126619
发货至: 中国

Quick Overview for Recombinant Cytokeratin 7 抗体 (AA 1-100) (ABIN7126619)

抗原

See all Cytokeratin 7 (KRT7) 抗体
Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Cytokeratin 7 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

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    AA 1-100

    特异性

    Cytokeratin 7 in humans is a protein encoded by the KRT7 gene. It is always as a keratin pair with Cytokeratin 19. Cytokeratin 7 is expressed on most ductal and glandular epithelium including lung, breast, bladder and female genital tract, but not in most gastrointestinal epithelium, prostate, hepatocyte and squamous epithelium. In tumor tissues, its expression is absent in colon cancer, prostate cancer and squamous carcinomas. Cytokeratin 7 is often used in concert with Cytokeratin 20 and CDX-2 to aid in distinguishing ovarian, pulmonary and breast carcinomas (CK7+) from colon carcinomas (CK7-).

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment (around aa1-100) of human KRT7 protein (exact sequence is proprietary)

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Carcinoma of ovary, lung, cervix, or breast.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

    别名

    KRT7

    背景

    CK-7, K2C7, Keratin 55K Type II Cytoskeletal, Keratin Simple Epithelial Type 1 K7, Keratin Type II Cytoskeletal 7, Krt2-7, KRT7, Sarcolectin, SCL, Type II Mesothelial Keratin K7, Type-II Keratin Kb7,Cytokeratin 7 (Glandular and Transitional Epithelial Marker)
    Cellular localisation: Cytoplasm

    分子量

    55kDa

    基因ID

    3855, 411501

    UniProt

    P08729
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