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Recombinant Interferon gamma 抗体

This anti-Interferon gamma antibody is a 兔 单克隆 antibody detecting Interferon gamma in IHC (f). Suitable for 人.
产品编号 ABIN7126540
发货至: 中国

Quick Overview for Recombinant Interferon gamma 抗体 (ABIN7126540)

抗原

See all Interferon gamma (IFNG) 抗体
Interferon gamma (IFNG)

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This Interferon gamma antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 特异性

    Recognizes a protein of 20-25 kDa, identified as human interferon. This MAb is specific to human IFN-i³ and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-i³. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-i±/i² (type I interferon).

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human IFNG protein

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: PMA stimulated human peripheral blood mononuclear cells. Renal or testicular carcinoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Interferon gamma (IFNG)

    别名

    IFNG

    背景

    AMCF1, Beta thromboglobulin like protein, CXC chemokine ligand 8 (CXCL8), Emoctakin, Granulocyte chemotactic protein 1 (GCP1), IFG, IFI, IFN Immune, Interleukin 8, LECT, LUCT, Lymphocyte derived neutrophil activating factor, LYNAP, Macrophage Activating Factor (MAF), Monocyte derived neutrophil activating protein (MONAP), Monocyte derived neutrophil chemotactic factor (MDNCF), Neutrophil activating factor (NAF), Neutrophil activating peptide 1 (NAP1), Neutrophil activating protein 1 (NAP1), SCYB8, T cell chemotactic factor, T Cell Interferon,Interferon gamma (IFNG)
    Cellular localisation: Cytoplasmic & Cell Surface

    分子量

    20-25kDa

    基因ID

    3458, 856

    UniProt

    P01579

    途径

    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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